Invitrogen™ NGAL Monoclonal Antibody (14)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ ABS0621402

Product Code. 15366301

Description

Reactivity: ABS 062-14-02 binds human NGAL coated onto a solid phase. ABS 062-14-02 can be used as a detection antibody in a sandwich ELISA with capture antibodies HYB 211-01-02, ABS 038-04-02, ABS 038-14-02, ABS 038-15-02, ABS 038-23-02, ABS 038-26-02 and ABS 062-33-02. When ABS 062-14-02 is used as a biotinylated detection antibody with capture antibody ABS 062-33-02, the assay is specific for the NGAL monomer, cross-reacting less than 1% with NGAL homodimer. NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL.

NGAL (Neutrophil gelatinase-associated lipocalin, lipocalin 2, siderocalin and neutrophil lipocalin) is a 25 kDa glycosylated single chain monomer and member of the lipocalin family of proteins that bind and transport small lipophilic molecules. NGAL is released by activated neutrophils, can form dimers and small amounts of higher oligomers, and complexes with matrix metalloproteinase 9 (MMP-9, gelatinase B). Low level expression of NGAL in a variety of epithelia may be increased in inflammation or cancers. Expression of NGAL in the kidney is dramatically increased by ischemic or nephrotoxic kidney injury.

Specifications

• Antigen: NGAL
• Classification: Monoclonal
• Concentration: 0.95 mg/mL
• Formulation: PBS with 15mM sodium azide; pH 7.4
• Gene Accession No.: P80188
• Gene Symbols: LCN2
• Immunogen: Human recombinant NGAL coupled to carrier and adsorbed to aluminium hydroxide gel.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a κ

• Applications: ELISA
• Clone: 14
• Conjugate: Unconjugated
• Gene: LCN2
• Gene Alias: 24p3; 25 kDa alpha-2-microglobulin-related subunit of MMP-9; alpha-2-microglobulin-related protein; Alpha-2U globulin-related protein; AW212229; HGNC:6526; HNL; LCN2; lipocalin 2; lipocalin 2 (oncogene 24p3); Lipocalin 24p3; Lipocalin2; Lipocalin-2; migration-stimulating factor inhibitor; MSFI; neutrophil gelatinase-associated lipocalin; NGAL; oncogene 24p3; OTTHUMP00000022240; p25; RP23-161B9.11; secreted inducible protein 24; Siderocalin; Siderocalin LCN2; Sip24; SV-40-induced 24P3 protein; uterocalin
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 3934
• Content And Storage: 4°C, store in dark
• Form: Liquid