Invitrogen™ NGAL Monoclonal Antibody (14)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ ABS0471402

Product Code. 15376291

Description

ABS 047-14-02 binds free canine NGAL. This antibody shows no cross-reaction with human, mouse ,or rat. ABS 047-14-02 can be used as a capture antibody in a sandwich ELISA using biotinylated detection antibody ABS 047-17-02, giving a detection limit of 5 pg/mL in an unoptimized buffer assay. NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL.

NGAL (Neutrophil gelatinase-associated lipocalin, lipocalin 2, siderocalin and neutrophil lipocalin) is a 25 kDa glycosylated single chain monomer and member of the lipocalin family of proteins that bind and transport small lipophilic molecules. NGAL is released by activated neutrophils, can form dimers and small amounts of higher oligomers, and complexes with matrix metalloproteinase 9 (MMP-9, gelatinase B). Low level expression of NGAL in a variety of epithelia may be increased in inflammation or cancers. Expression of NGAL in the kidney is dramatically increased by ischemic or nephrotoxic kidney injury.

Specifications

• Antigen: NGAL
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 15 mM sodium azide; pH 7.4
• Gene Accession No.: 0
• Gene Symbols: LCN2
• Immunogen: Recombinant dog NGAL adsorbed onto aluminum hydroxide gel.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Canine
• Product Type: Antibody
• Isotype: IgG2b κ

• Applications: ELISA, Immunohistochemistry, Western Blot
• Clone: 14
• Conjugate: Unconjugated
• Gene: LCN2
• Gene Alias: 24p3; 25 kDa alpha-2-microglobulin-related subunit of MMP-9; alpha-2-microglobulin-related protein; Alpha-2U globulin-related protein; AW212229; HGNC:6526; HNL; LCN2; lipocalin 2; lipocalin 2 (oncogene 24p3); Lipocalin 24p3; Lipocalin2; Lipocalin-2; migration-stimulating factor inhibitor; MSFI; neutrophil gelatinase-associated lipocalin; NGAL; oncogene 24p3; OTTHUMP00000022240; p25; RP23-161B9.11; secreted inducible protein 24; Siderocalin; Siderocalin LCN2; Sip24; SV-40-induced 24P3 protein; uterocalin
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 491320
• Content And Storage: 4°C, store in dark
• Form: Liquid