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NG 52, MedChemExpress

Product Code. 16422447
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Product Code. 16422447 Supplier Medchem Express Supplier No. HY15154

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Description

MedChemExpress NG 52 is a potent, cell-permeable, selective, ATP-compatible and orally active Cdc28p and Pho85p kinase inhibitor with IC50s of 7 μM and 2 μM, respectively. NG 52 also inhibits the activity of phosphoglycerate kinase 1 (PGK1) with an IC50 of 2.5 μM. NG 52 is inactive against yeast kinases Kin28p, Srb10, and Cak1p.

NG 52 is a potent, cell-permeable, selective, ATP-compatible and orally active Cdc28p and Pho85p kinase inhibitor with IC50s of 7 μM and 2 μM, respectively. NG 52 also inhibits the activity of phosphoglycerate kinase 1 (PGK1) with an IC50 of 2.5 μM. NG 52 is inactive against yeast kinases Kin28p, Srb10, and Cak1p.

Specifications

Chemical Name or Material NG 52
CAS 212779-48-1
Color White
Purity Grade Notes Research
Molecular Formula C16H19ClN6O
Quantity 50 mg
Synonym Compound 52
Solubility Information DMSO : 100 mg/mL (288.34 mM; Need ultrasonic)
SMILES ClC1=CC(NC2=NC(NCCO)=NC3=C2N=CN3C(C)C)=CC=C1
Molecular Weight (g/mol) 346.81
Formula Weight 346.81
Percent Purity 99.91%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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