Invitrogen™ NFYA Recombinant Rabbit Monoclonal Antibody (K01_1U78)

Product Code.	Quantity	Unit Size
30829397	100 μL	100µL
30825801	50 μL	-

Product Code. 30829397 Supplier Invitrogen™ Supplier No. MA563681

Description

Rabbit Recombinant Monoclonal Antibody

NFYA Recombinant Monoclonal Antibody for Western Blot

The NFYA gene encodes for one of the subunits of the Nuclear Factor Y (NF-Y) transcription factor, which plays a critical role in the regulation of various genes, particularly those containing the CCAAT box within their promoter regions. Structurally, NF-Y consists of a heterotrimeric complex made up of NF-YA, NF-YB, and NF-YC subunits. NF-YA serves as the sequence-specific DNA-binding component, whereas the NF-YB/NF-YC heterodimer forms a Histone Fold Domain crucial for DNA binding and stabilization. Functionally, NF-YA is pivotal in cell cycle regulation and neuronal development, influencing neural progenitor maintenance during brain morphogenesis. It has been implicated in various physiological processes, including response to plant stress and cancer progression. Specifically, NFYA gene activity is prevalent in proliferating cells and is often dysregulated in cancerous tissues, which highlights its potential as a therapeutic target. NFYA's expression in plant systems, such as in the Arabidopsis species, is modulated by environmental stresses like drought, indicating its broader impact on biological stress responses.

Specifications

• Antigen: NFYA
• Applications: Western Blot
• Classification: Recombinant Monoclonal
• Clone: K01_1U78
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: 50mM tris glycine with 0.05% BSA, 150mM NaCl, 40% glycerol and 0.01% sodium azide; pH 7.4
• Gene: NFYA
• Gene Accession No.: P18576, P23511, P23708
• Gene Alias: AA407810; CAAT box DNA-binding protein subunit A; CAAT-box DNA binding protein subunit A; CAAT-box DNA-binding protein subunit A; CBF-A; Cbf-b; CCAAT-binding transcription factor subunit A; CCAAT-binding transcription factor subunit B; FLJ11236; HAP2; HAP2 CCAAT-binding protein; nf-y; NFYA; NF-YA; Nuclear transcription factor Y subunit A; nuclear transcription factor Y subunit alpha; nuclear transcription factor Y, alpha; nuclear transcription factor-Y alpha; SEZ10; SEZ-10; Transcription factor NF-Y, A subunit
• Gene Symbols: NFYA
• Host Species: Rabbit
• Immunogen: A synthetic peptide of human NFYA.
• Purification Method: Protein A/G
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 18044, 29508, 4800
• Target Species: Human, Mouse, Rat
• Content And Storage: Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG