Invitrogen™ NFKBIL2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA555153

Product Code. 15793071

Description

Immunogen sequence: WNRRNDMGET LLHRACIEGQ LRRVQDLVRQ GHPLNPRDYC GWTPLHEACN YGHLEIVRFL LDHGAAVDDP GGQGCEGITP LHDALNCGHF EVAELLLERG ASVTLRTRK Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.

The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus.

Specifications

• Antigen: NFKBIL2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TONSL
• Gene Alias: DNA repair protein; ikappaBR; I-kappa-B-related protein; IKBR; Inhibitor of kappa B-related protein; NF-kappa-B inhibitor-like protein 2; NFKBIL2; Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2; TONSL; tonsoku-like; Tonsoku-like protein; tonsoku-like, DNA repair protein
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4796
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q96HA7
• Gene Symbols: TONSL
• Immunogen: Recombinant protein corresponding to Human NFKBIL2. Recombinant protein control fragment (Product #RP-89378).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG