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Invitrogen™ NF-H Polyclonal Antibody
Description
This antibody reacts primarily with the phosphorylated axonal form of NF-H and shows some cross-reactivity with phosphorylated NF-M, which has similar phosphorylation sites to NF-H.
Involved in the maintenance of neuronal caliber, neurofilaments are the intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. Like most other intermediate filament proteins (IFPs), the expression of the different neuronal IFPs is both tissue-specific and developmentally regulated. NF-H has an important role in mature axons and is involved in amyotrophic lateral sclerosis (ALS).
Specifications
Specifications
| Antigen | NF-H |
| Applications | ELISA, Immunohistochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Multiplex Immunohistochemistry |
| Classification | Polyclonal |
| Concentration | Conc. Not Determined |
| Conjugate | Unconjugated |
| Formulation | PBS with 0.02% sodium azide |
| Gene | Nefh |
| Gene Accession No. | P12036, P12037, P16884, P19246 |
| Gene Alias | 200 kDa neurofilament protein; CMT2CC; heavy neurofilament protein; I79_012512; intermediate filament protein; KIAA0845; LOW QUALITY PROTEIN: neurofilament heavy polypeptide; mKIAA0845; NEF3; Nefh; nefh.L; neurofilament; neurofilament 200kDa; neurofilament heavy; neurofilament heavy L homeolog; neurofilament heavy polypeptide; neurofilament heavy polypeptide-like; neurofilament triplet H protein; neurofilament, heavy polypeptide; neurofilament, heavy polypeptide 200kDa; neurofilament, heavy polypeptide L homeolog; neurofilament-H; NF 200 kD; NF200; Nfh; NF-H; NHC; XELAEV_18007418mg |
| Gene Symbols | Nefh |
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