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Invitrogen™ NF-H Monoclonal Antibody (NF-05)
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Product Code. 12322443
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Quantity:
100 μg
Unit Size:
Pack of 100
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12322443 100 μg Pack of 100
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Product Code. 12322443 Supplier Invitrogen™ Supplier No. MA110441

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Description

Mouse Monoclonal Antibody

This antibody recognizes a nonphosphorylated epitope of neurofilament heavy protein (NF-H), a 210 kDa intracellular structural protein of Intermediate Filament Proteins family. NF-H is mainly expressed in the central and peripheral nervous system and reproductive system and is biochemically very stable. It will not cross-react with mouse.

Involved in the maintenance of neuronal caliber, neurofilaments are the intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. Like most other intermediate filament proteins (IFPs), the expression of the different neuronal IFPs is both tissue-specific and developmentally regulated. NF-H has an important role in mature axons and is involved in amyotrophic lateral sclerosis (ALS).
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Specifications

Antigen NF-H
Applications ELISA, Immunohistochemistry (Frozen), Western Blot
Classification Monoclonal
Clone NF-05
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 15mM sodium azide; pH 7.4
Gene Nefh
Gene Accession No. P12036, P12037, P16884
Gene Alias 200 kDa neurofilament protein; CMT2CC; heavy neurofilament protein; I79_012512; intermediate filament protein; KIAA0845; LOW QUALITY PROTEIN: neurofilament heavy polypeptide; mKIAA0845; NEF3; Nefh; nefh.L; neurofilament; neurofilament 200kDa; neurofilament heavy; neurofilament heavy L homeolog; neurofilament heavy polypeptide; neurofilament heavy polypeptide-like; neurofilament triplet H protein; neurofilament, heavy polypeptide; neurofilament, heavy polypeptide 200kDa; neurofilament, heavy polypeptide L homeolog; neurofilament-H; NF 200 kD; NF200; Nfh; NF-H; NHC; XELAEV_18007418mg
Gene Symbols Nefh
Host Species Mouse
Immunogen Pig brain neurofilament protein-enriched fraction after depolymerization of microtubules.
Purification Method Sequential Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100156492, 24587, 4744
Target Species Human, Rat, Pig
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgG1
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