Invitrogen™ Neuropilin 2 Polyclonal Antibody

Goat Polyclonal Antibody

Brand:  Invitrogen™ PA547274

Product Code. 15587762

Description

In direct ELISAs, approximately 50% cross-reactivity with recombinant mouse Neuropilin-2 is observed, and approximately 25% cross-reactivity with recombinant rat (rr) Neuropilin-2 is observed and less than 5% cross-reactivity with rrNeuropilin-1 is observed. Reconstitute at 0.2 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.

This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein (sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C) and SEMA3F protein (sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F), and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Specifications

• Antigen: Neuropilin 2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NRP2
• Gene Alias: 1110048P06Rik; neuropilin 2; neuropilin-2; neuropilin-2a(17); neuropilin-2a(22); neuropilin-2b(0); Np2; Np-2; Npn2; Npn-2; NRP2; PRO2714; receptor for VEGF165 and semaphorins class3; vascular endothelial cell growth factor 165 receptor 2; VEGF165R2
• Host Species: Goat
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18187, 81527, 8828
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Neutralization, Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: O35276, O35375, O60462
• Gene Symbols: NRP2
• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Neuropilin-2 Gln23-Tyr855.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG