Invitrogen™ Neurogenin 2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA534472

Product Code. 15335401

Description

A suggested positive control is mouse small intestine tissue lysate. PA5-34472 can be used with blocking peptide PEP-1514.

Neurogenin-2 is a member of the neurogenin subfamily of basic helix-loop-helix (bHLH) transcription factor genes that play an important role in neurogenesis from migratory neural crest cells. In the course of mouse neurogenesis, Ngn2 and Ngn1 are expressed in distinct progenitor populations residing in the central and peripheral nervous systems. Mutation analyses demonstrate that Ngn1 is required for the determination of neuronal precursors for proximal cranial sensory ganglia and that Ngn2 is necessary for the determination of precursors for epibranchial placode-derived sensory neurons.

Specifications

• Antigen: Neurogenin 2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NEUROG2
• Gene Alias: Ath4a; ATOH4; atonal homolog 4; bHLHa8; Class A basic helix-loop-helix protein 8; helix-loop-helix protein mATH-4A; mATH4A; NEUROG2; neurogenin 2; neurogenin2; neurogenin-2; NGN2; NGN-2; Protein atonal homolog 4
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11924, 295475, 63973
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: P70447, Q9H2A3
• Gene Symbols: NEUROG2
• Immunogen: A 19 amino acid peptide near the carboxy terminus of human NGN2.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG