Invitrogen™ Neurogenin 1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Marca:  Invitrogen™ PA5102697

Código de producto. 16679154

Descripción

Antibody detects endogenous levels of total NEUROG1.

Neurogenin 1 is a basic helix-loop-helix (bHLH) proteins are transcription factors involved in determining cell type during development. NeuroG1 is a bHLH protein with dual cell-fate specification roles. It functions during neurogenesis, and it has also been shown to inhibit the differentiation of neural stem cells into astrocytes. NeuroG1 promotes neurogenesis by functioning as a transcriptional activator, yet it inhibits astrocyte differentiation by compartmentalizing the CREB-binding protein transcription complex away from astrocyte differentiation genes and by inhibiting STAT transcription factors essential for gliogenesis.

Especificaciones

• Antigen: Neurogenin 1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NEUROG1
• Gene Alias: AKA; ATH4C; basic helix-loop-helix transcription factor; bHLHa6; cb260; chunp6899; class A basic helix-loop-helix protein 6; Helix-loop-helix protein mATH-4C; Math4C; Neurod3; NEUROG1; Neurogenic basic-helix-loop-helix protein; neurogenic differentiation 3; neurogenic differentiation factor 3; neurogenin; neurogenin 1; neurogenin related protein-1; neurogenin-1; Neurogenin-related protein 1; NGN; Ngn1; NGN-1; ngr1; transcription factor; Zath4c; zNgn1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18014, 29410, 4762
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P70595, P70660, Q92886
• Gene Symbols: NEUROG1
• Immunogen: A synthesized peptide derived from human NEUROG1(Accession Q92886), corresponding to amino acid residues A137-G187.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG