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Invitrogen™ Neuritin Polyclonal Antibody

Product Code. 12848552
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Quantity:
100 μg
Unit Size:
100µg
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12848552 100 μg 100µg
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Product Code. 12848552 Supplier Invitrogen™ Supplier No. PA520368

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Description

Rabbit Polyclonal Antibody

A suggested positive control is Daudi cell lysate. PA5-20368 can be used with blocking peptide PEP-0482.

Neuritin belongs to the neuritin family and is expressed in postmitotic-differentiating neurons of the developmental nervous system as well as neuronal structures associated with plasticity in adults. Its expression can be induced by neural activity and neurotrophins. The protein contains a consensus cleavage signal found in glycosylphoshatidylinositol (GPI)-anchored proteins and promotes neurite outgrowth and arborization, indicating its role in promoting neuritogenesis. Overexpression of the protein may be associated with astrocytoma progression. Alternative splicing leads to multiple transcript variants. NRN1 is associated with Severe Congenital Neutropenia 8 and Spinal Muscular Atrophy, Type III.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Neuritin
Applications Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene NRN1
Gene Accession No. Q8CFV4, Q9NPD7
Gene Alias 0710008J23Rik; Candidate plasticity gene 15 protein; candidate plasticity-related gene 15; Cpg15; dJ380B8.2; Neuritin; neuritin 1; NRN; NRN1
Gene Symbols NRN1
Host Species Rabbit
Immunogen A 20 amino acid peptide from near the center of human neuritin.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51299, 68404
Target Species Human, Mouse
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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