Invitrogen™ Neuritin Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5145396

Product Code. 17988692

Description

Neuritin belongs to the neuritin family and is expressed in postmitotic-differentiating neurons of the developmental nervous system as well as neuronal structures associated with plasticity in adults. Its expression can be induced by neural activity and neurotrophins. The protein contains a consensus cleavage signal found in glycosylphoshatidylinositol (GPI)-anchored proteins and promotes neurite outgrowth and arborization, indicating its role in promoting neuritogenesis. Overexpression of the protein may be associated with astrocytoma progression. Alternative splicing leads to multiple transcript variants. NRN1 is associated with Severe Congenital Neutropenia 8 and Spinal Muscular Atrophy, Type III.

Specifications

• Antigen: Neuritin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NRN1
• Gene Alias: 0710008J23Rik; Candidate plasticity gene 15 protein; candidate plasticity-related gene 15; Cpg15; dJ380B8.2; Neuritin; neuritin 1; NRN; NRN1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 100155948, 51299
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% Proclin 300; pH 7.4
• Gene Accession No.: Q9NPD7
• Gene Symbols: NRN1
• Immunogen: Recombinant Human NRN1 protein, Ala28-Phe142 (Accession #Q9NPD7).
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human, Pig
• Product Type: Antibody
• Isotype: IgG