Nestin Mouse anti-Human, Clone: 10C2, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-9843-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15298187

Quantity Price
1 £ 170.59 / 100µg
Estimated Shipment date
from Supplier 08-05-2017
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Description and Specification

Specification

Applications Immunocytochemistry
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Immunohistochemistry (Frozen)
Applications Microscopy
Applications Western Blotting
Species Reactivity Human
Quantity 100μg
Clone 10C2
Concentration 0.5mg/mL
Antigen Nestin
Primary or Secondary Primary
Regulatory Status RUO
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Conjugate Unlabeled
Format Purified
Isotype IgG1
Host Species Mouse
Storage Requirements Store at 2-8°C.
Monoclonal or Polyclonal Monoclonal

The monoclonal antibody 10C2 recognizes human nestin (residues 1464-1614). Nestin is a 220-240kDa Class VI intermediate filament protein that is expressed in stem cells of the developing nervous system. Expression has also been found in pancreatic islet and mesenchymal precursors in addition to cells with angiogenic potential. Upon differentiation, nestin-containing filaments are replaced by cell type-specific intermediate filament proteins, such as GFAP. Expression has been identified in a variety of cancerous cells including glioblastomas and pancreatic tumors. No cross-reactivity to rodent nestins has been observed using the 10C2 antibody.