Nestin Mouse anti-Human, Clone: 10C2, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-9843-82

100UG:ANTI-HUMAN NESTIN PURIFIED 100 UG

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15298187

Quantity Price
1 £ 201.0 / 100µg
Estimated Shipment date
from Supplier 23-01-2017
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Description and Specification

Specification

Antigen Nestin
Applications Immunocytochemistry
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Immunohistochemistry (Frozen)
Applications Microscopy
Applications Western Blotting
Clone 10C2
Concentration 0.5mg/mL
Conjugate Unlabeled
Format Purified
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Host Species Mouse
Isotype IgG1
Quantity 100μg
Regulatory Status RUO
Species Reactivity Human
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal

The monoclonal antibody 10C2 recognizes human nestin (residues 1464-1614). Nestin is a 220-240kDa Class VI intermediate filament protein that is expressed in stem cells of the developing nervous system. Expression has also been found in pancreatic islet and mesenchymal precursors in addition to cells with angiogenic potential. Upon differentiation, nestin-containing filaments are replaced by cell type-specific intermediate filament proteins, such as GFAP. Expression has been identified in a variety of cancerous cells including glioblastomas and pancreatic tumors. No cross-reactivity to rodent nestins has been observed using the 10C2 antibody.