Nestin Mouse anti-Human, Clone: 10C2, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-9843-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15288187

Quantity Price
1 £ 66.65 / 25µg
Estimated Shipment date
from Supplier 04-05-2017
Add to basket


Description and Specification

Specification

Primary or Secondary Primary
Concentration 0.5mg/mL
Monoclonal or Polyclonal Monoclonal
Applications Immunocytochemistry
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Immunohistochemistry (Frozen)
Applications Microscopy
Applications Western Blotting
Regulatory Status RUO
Species Reactivity Human
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Quantity 25μg
Storage Requirements Store at 2-8°C.
Conjugate Unlabeled
Format Purified
Host Species Mouse
Clone 10C2
Antigen Nestin
Isotype IgG1

The monoclonal antibody 10C2 recognizes human nestin (residues 1464-1614). Nestin is a 220-240kDa Class VI intermediate filament protein that is expressed in stem cells of the developing nervous system. Expression has also been found in pancreatic islet and mesenchymal precursors in addition to cells with angiogenic potential. Upon differentiation, nestin-containing filaments are replaced by cell type-specific intermediate filament proteins, such as GFAP. Expression has been identified in a variety of cancerous cells including glioblastomas and pancreatic tumors. No cross-reactivity to rodent nestins has been observed using the 10C2 antibody.