Invitrogen™ Neogenin Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA555695

Product Code. 15783611

Description

Immunogen sequence: SVNGSHKYKG NSKDVKPPDL WIHHERLELK PIDKSPDPNP IMTDTPIPRN SQDITPVDNS MDSNIHQRRN SYRGHESEDS MSTLAGR Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.

The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Specifications

• Antigen: Neogenin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Neo1
• Gene Alias: 2610028H22Rik; AI327052; D930014N22Rik; HsT17534; IGDCC2; immunoglobulin superfamily DCC subclass member 2; NEO; Neo1; Neogenin; neogenin 1; neogenin homolog 1; NGN; NGNDKFZp547A066; NTN1R2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4756
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q92859
• Gene Symbols: Neo1
• Immunogen: Recombinant protein corresponding to Human Neogenin. Recombinant protein control fragment (Product #RP-95257).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG