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Invitrogen™ NENF Polyclonal Antibody

Product Code. 12858752
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Quantity:
100 μg
Unit Size:
100µg
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12858752 100 μg 100µg
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Product Code. 12858752 Supplier Invitrogen™ Supplier No. PA520577

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Description

Rabbit Polyclonal Antibody

Despite its predicted molecular weight of ~20kDa, NENF is observed at 37kDa in SDS-PAGE. A suggested positive control is human small intestine tissue lysate. PA5-20577 can be used with blocking peptide PEP-0697.

NENF is a secreted protein that is expressed in neurons but not glial cells of the brain. This protein has neurotrophic activity in primary cultured mouse neurons but not mitogenic activity in primary cultured mouse astrocytes. NENF activated mitogen-activated protein (MAP) and phosphotidylinositol-3 kinase pathways and could be inhibited by pertussis toxin but not receptor tyrosine kinases, suggesting that NENF acts through a Gi/Go-protein-coupled receptor.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NENF
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene NENF
Gene Accession No. Q6IUR5, Q9CQ45, Q9UMX5
Gene Alias 1110060M21Rik; cell growth-inhibiting protein 47; cell immortalization-related protein 2; CIR2; NENF; nenf {ECO:0000250; Neudesin; neudesin neurotrophic factor; neuron derived neurotrophic factor; neuron-derived neurotrophic factor; Protein GIG47; SCIRP10; SCIRP10-related protein; secreted protein of unknown function; sp2; SP2 protein; Spinal cord injury related protein 10; spinal cord injury-related protein 10; SPUF; SPUF protein; UniProtKB:Q9CQ45}; wu:fa11a04; wu:fb73f07; zgc:112953; zgc:112953 protein; zgc:152703
Gene Symbols NENF
Host Species Rabbit
Immunogen A 15 amino acid peptide from near the carboxy terminus of human NENF.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 289380, 29937, 66208
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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