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  6. Necrostatin-1, MedChemExpress

Necrostatin-1, MedChemExpress

Product Code. p-200099503
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Product Code. 16496916

Brand: Medchem Express HY15760

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Description

MedChemExpress Necrostatin-1 (Nec-1) is a potent and cross the blood-brain barrier necroptosis inhibitor with an EC50 of 490 nM in Jurkat cells. Necrostatin-1 inhibits RIP1 kinase (EC50=182 nM). Necrostatin-1 is also an IDO inhibitor.

Necrostatin-1 (Nec-1) is a potent and cross the blood-brain barrier necroptosis inhibitor with an EC50 of 490 nM in Jurkat cells. Necrostatin-1 inhibits RIP1 kinase (EC50=182 nM). Necrostatin-1 is also an IDO inhibitor.

Specifications

Chemical Name or Material Necrostatin-1
Physical Form Powder
CAS 4311-88-0
Color Yellow
Quantity 100 mg
Purity Grade Notes Research
Molecular Formula C13H13N3OS
For Use With (Application) Cancer-Kinase/protease
Synonym Nec-1
Solubility Information DMSO : ≥ 46 mg/mL (177.38 mM)
SMILES O=C(C(CC1=CNC2=C1C=CC=C2)N3)N(C)C3=S
Molecular Weight (g/mol) 259.33
Formula Weight 259.33
Percent Purity 98.96%
Grade Research
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Research purposes only

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