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Tocris Bioscience™ Nebivolol hydrochloride
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Product Code. 18095182
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 18095182

Brand: Tocris Bioscience™ 3517/10

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This item is not returnable. View return policy

Description

Highly selective β1-adrenoceptor antagonist

Highly selective β1-adrenoceptor antagonist (Ki values are 0.88, 20, 44, 700, 1160, 2400 and 4000 nM at β1, 5-HT1A, β2, 5-HT2, α1, H1 and D2 receptors respectively). Induces vasodilation via a nitric oxide- and cGMP-dependent mechanism (EC50 = 11.36 μM in renal arteries) and displays antihypertensive activity in vivo. GRK/β -arrestin biased agonist at the β2 adrenoceptor.
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Chemical Identifiers

CAS 152520-56-4
Molecular Formula C22H26ClF2NO4

Specifications

Quantity 10 mg
Formula Weight 441.9
Purity >98%
Molecular Weight (g/mol) 445.924
Chemical Name or Material Nebivolol hydrochloride
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