Invitrogen™ NDUFS4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA552010

Product Code. 15779960

Description

Immunogen sequence: RSLRTSTWRL AQDQTQDTQL ITVDEKLDIT TLTGVPEEHI KTRKVRIFVP ARNNMQSGVN NTKKWKMEFD TRERWENPLM GWASTADPLS NMVLTFSTKE DAVSFAEKNG WSYDIEERKV PKPKSKSYGA NFSWNKRTRV S Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 91%.

This gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), or NADH:ubiquinone oxidoreductase, the first multi-subunit enzyme complex of the mitochondrial respiratory chain. Complex I plays a vital role in cellular ATP production, the primary source of energy for many crucial processes in living cells. It removes electrons from NADH and passes them by a series of different protein-coupled redox centers to the electron acceptor ubiquinone. In well-coupled mitochondria, the electron flux leads to ATP generation via the building of a proton gradient across the inner membrane. Complex I is composed of at least 41 subunits, of which 7 are encoded by the mitochondrial genome and the remainder by nuclear genes.

Specifications

• Antigen: NDUFS4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NDUFS4
• Gene Alias: 6720411N02Rik; AQDQ; C1-18k; CI-18; CI-18 kDa; CI-AQDQ; complex I 18kDa subunit; complex I-18 kDa; Complex I-AQDQ; mitochondrial respiratory chain complex I (18-KD subunit); NADH dehydrogenase (ubiquinone) Fe-S protein 4; NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase); NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial; NADH:ubiquinone oxidoreductase subunit S4; NADH-ubiquinone oxidoreductase 18 kDa subunit; NDUFS4
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 17993, 4724, 499529
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O43181, Q5XIF3, Q9CXZ1
• Gene Symbols: NDUFS4
• Immunogen: Recombinant protein corresponding to Human NDUFS4. Recombinant protein control fragment (Product #RP-102243).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG