Invitrogen™ NDUFS2 Polyclonal Antibody

Goat Polyclonal Antibody

Brand:  Invitrogen™ PA519342

Product Code. 11327323

Description

This antibody is predicted to react with bovine, canine, porcine and rabbit based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000.

The protein encoded by this gene is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase. Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes. The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product. Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: NDUFS2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Ndufs2
• Gene Alias: AL033311; CI-49; CI-49kD; comp; complex 1, mitochondrial respiratory chain, 49-KD subunit; complex I 49kDa subunit; complex I-49kD; EMBL:AAH82067.1}; NADH dehydrogenase (ubiquinone) Fe-S protein 2; NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase); NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial; NADH:ubiquinone oxidoreductase core subunit S2; NADH-coenzyme Q reductase; NADH-ubiquinone oxidoreductase 49 kDa subunit; NADH-ubiquinone oxidoreductase NDUFS2 subunit; Ndufs2; ndufs2 {ECO:0000312; unnamed protein product
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 226646, 289218, 4720
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O75306, Q641Y2, Q91WD5
• Gene Symbols: Ndufs2
• Immunogen: Synthetic peptide sequence (SRGVRQWQPDVE) corresponding to the internal amino acids of NDUFS2 (aa 31-42).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG