Invitrogen™ NDRG1 Polyclonal Antibody

Goat Polyclonal Antibody

Brand:  Invitrogen™ PA518109

Product Code. 11326083

Description

This antibody is predicted to react with canine, mouse and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.

NDRG1 is a 394 amino acid cytoplasmic protein belonging to the NDRG family. It interacts with APO A-I and A-II and plays a role in HDL-mediated cholesterol transport, stress responses, hormone responses, cell growth and differentiation. Its defect causes Charcot-Marie-Tooth disease type 4D (CMT4D) that is characterized by reduced nerve conduction velocities, segmental demyelination and remyelination with onion bulb formations on nerve biopsy, slowly progressive distal muscle atrophy and weakness, absent deep tendon reflexes and hollow feet. NDRG1 plays a growth inhibitory role and serves as a marker of differentiation. It is expressed in placental membranes, prostate, kidney, small intestine, ovary tissues, colon and the cells that border the lumen.

Specifications

• Antigen: NDRG1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NDRG1
• Gene Alias: CAP43; CMT4D; differentiation-related gene 1 protein; DRG1; DRG-1; GC4; HMSNL; Ndr1; Ndrg1; Ndrl; nickel-specific induction protein Cap43; NMSL; N-myc downstream regulated 1; N-myc downstream regulated gene 1; N-myc downstream-regulated gene 1 protein; Protein Ndr1; protein NDRG1; protein regulated by oxygen-1; PROXY1; Reducing agents and tunicamycin-responsive protein; Rit42; RTP; TARG1; TDD5
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 10397
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q92597
• Gene Symbols: NDRG1
• Immunogen: Synthetic peptide sequence (GNSAGPKSMEVSC) corresponding to the C-terminus amino acids of NDRG1 (aa 382-394).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG