Invitrogen™ NDE1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA554972

Product Code. 15722901

Description

Immunogen sequence: KDEARDLRQE LAVQQKQEKP RTPMPSSVEA ERTDTAVQAT GSVPSTPIAH RGPSSSLNTP GSFRRGLDDS TGGTPLTPAA RISALNIVGD LLRKVGALES KLAS Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 83%.

NDE1 is s a member of the nuclear distribution E (NudE) family of proteins. It is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. NDE1 protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations to the gene lead to Lissencephaly 4 (LIS4) and Microhydranencephaly (MHAC).

Specifications

• Antigen: NDE1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NDE1
• Gene Alias: 2810027M15Rik; AU042936; AW822251; HOM-TES-87; LIS1-interacting protein NUDE1; LIS1-interacting protein NUDE1, rat homolog; LIS4; MHAC; mNudE; NDE; NDE1; nuclear distribution gene E homolog 1; nuclear distribution gene E homolog 1 (A nidulans); nuclear distribution protein nudE homolog 1; NudE; nudE neurodevelopment protein 1; nudE nuclear distribution E homolog 1; nudE nuclear distribution gene E homolog 1; Nude1; rNudE
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 54820, 67203, 83836
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9CZA6, Q9ES39, Q9NXR1
• Gene Symbols: NDE1
• Immunogen: Recombinant protein corresponding to Human NDE1. Recombinant protein control fragment (Product #RP-92277).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG