Invitrogen™ NBPF4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA560907

Product Code. 15708731

Description

Immunogen sequence: RLSQELPEVK EQEVPEDSVN EVYLTPSVHH DVSDCHQPYS STLSSLEDQL ACSALDVASP TEAACPQGTW SGDLSHH Highest antigen sequence identity to the following orthologs: Mouse - 32%, Rat - 32%.

This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number variations in the human chromosomal region 1q21.1, where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, mental retardation, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This gene family contains numerous pseudogenes. [provided by RefSeq, Mar 2013].

Specifications

• Antigen: NBPF4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NBPF4
• Gene Alias: NBPF4; Neuroblastoma breakpoint family member 4; neuroblastoma breakpoint family, member 4
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 148545
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q96M43
• Gene Symbols: NBPF4
• Immunogen: Recombinant protein corresponding to Human NBPF4. Recombinant protein control fragment (Product #RP-104380).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG