Invitrogen™ NBPF12 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5116360

Product Code. 17127598

Description

NBPF12 Polyclonal Antibody for Western Blot

This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number variations in the human chromosomal region 1q21.1, where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, cognitive disability, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This gene family contains numerous pseudogenes.

Specifications

• Antigen: NBPF12
• Classification: Polyclonal
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: Q5TAG4
• Gene Symbols: NBPF12
• Immunogen: KLH conjugated synthetic peptide between 148-181 amino acids from the Central region of human NBPF12.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Conjugate: Unconjugated
• Gene: NBPF12
• Gene Alias: chomosome one amplified sequence 1 cyclophilin; chromosome 1 amplified sequence 1; COAS1; KIAA1245; NBPF12; Neuroblastoma breakpoint family member 12; neuroblastoma breakpoint family, member 12
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 149013
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid