Invitrogen™ NBPF Pan Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5101712

Product Code. 16678184

Description

Antibody detects endogenous levels of total NBPF1/9/10/12/14/15/16/20.

This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number variations in the human chromosomal region 1q21.1, where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, mental retardation, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This gene family contains numerous pseudogenes. [provided by RefSeq, Apr 2013].

Specifications

• Antigen: NBPF Pan
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NBPF9
• Gene Alias: AB13; AB14; AB23; AB6; AD2; AE01; AE5; AG1; AG3; chomosome one amplified sequence 1 cyclophilin; chromosome 1 amplified sequence 1; COAS1; DJ328E19.C1.1; KIAA1245; KIAA1693; NBFP10; NBFP12; NBFP14; NBFP15; NBFP16; NBFP20; NBFP9; NBG; NBPF; NBPF1; NBPF10; NBPF12; NBPF14; NBPF15; NBPF16; NBPF20; NBPF9; Neuroblastoma breakpoint family member 1; neuroblastoma breakpoint family member 10; neuroblastoma breakpoint family member 12; neuroblastoma breakpoint family member 14; neuroblastoma breakpoint family member 15; Neuroblastoma breakpoint family member 16; neuroblastoma breakpoint family member 20; Neuroblastoma breakpoint family member 9; neuroblastoma breakpoint family, member 1; neuroblastoma breakpoint family, member 10; neuroblastoma breakpoint family, member 12; neuroblastoma breakpoint family, member 14; neuroblastoma breakpoint family, member 15; neuroblastoma breakpoint family, member 16; neuroblastoma breakpoint family, member 20; neuroblastoma breakpoint family, member 9
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100132406, 100288142, 149013, 25832, 284565, 400818, 55672
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P0DPF2, P0DPF3, Q3BBV0, Q5TAG4, Q5TI25, Q6P3W6, Q8N660
• Gene Symbols: NBPF1, NBPF10, NBPF12, NBPF14, NBPF15, NBPF20, NBPF9
• Immunogen: A synthesized peptide derived from human NBPF1(Accession Q3BBV0), corresponding to amino acid residues L1075-E1125.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG