NBN Mouse anti-Human, Clone:7E4C2, Abnova™

Mouse monoclonal antibody raised against recombinant human NBN.

Brand:  Abnova MAB17791.100ug

Product Code. 16095066

Description

Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq]

Specifications

• Antigen: NBN
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:10000)
  Flow Cytometry (1:200-1:400)
  Immunocytochemistry (1:200-1:1000)
  Immunohistochemistry (1:200-1:1000)
  Western Blot (1:500-1:2000)
  The optimal working dilution should be determined by the end user.
• Gene: NBN
• Host Species: Mouse
• Quantity: 100 μg
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
• Clone: 7E4C2
• Description: nibrin
• Formulation: In PBS (0.05% sodium azide)
• Gene Alias: AT-V1, AT-V2, ATV, FLJ10155, MGC87362, NBS, NBS1, P95
• Immunogen: Recombinant protein corresponding to amino acids 467-615 of human NBN from E. coli.
• Gene ID (Entrez): 4683
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid