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Tocris Bioscience™ NAV 2729
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Product Code. 18755999
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18755999 50 mg 50mg
18730128 10 mg 10mg
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Product Code. 18755999 Supplier Tocris Bioscience™ Supplier No. 5986/50

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Description

Selective ARF6 inhibitor

NAV 2729 is a selective ARF6 inhibitor (IC50 = 1.0 μM). Selective for ARF6 over other ARF family members and small GTPases. Inhibits ARF6 activation in uveal melanoma cells in vitro and blocks downstream signaling pathways of oncogenic GNAQ. Reduces tumorigenesis in mouse model of uveal melanoma.
TRUSTED_SUSTAINABILITY

Specifications

CAS 419547-11-8
Quantity 50 mg
Solubility Soluble to 100mM in DMSO
Molecular Formula C25H17ClN4O3
Formula Weight 456.88g/mol
Color Yellow
Product Type Inhibitor

For Research Use Only

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