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Invitrogen™ NALP8 Polyclonal Antibody

Product Code. 12819172
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Quantity:
100 μg
Unit Size:
100µg
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Product Code. Quantity unitSize
12819172 100 μg 100µg
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Product Code. 12819172 Supplier Invitrogen™ Supplier No. PA521024

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Description

Rabbit Polyclonal Antibody

A suggested positive control is human colon tissue lysate. PA5-21024 can be used with blocking peptide PEP-1138.

NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP8 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It maps to chromosome 19q13.42 and is thought to be expressed in testis and ovary, suggesting that NALP8 may be involved in reproduction. Surprisingly, NALP8 seems to be universal in mammals except for rodents, suggesting that the gene may have been lost during evolution.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NALP8
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene NLRP8
Gene Accession No. Q86W28
Gene Alias CLR19.2; NACHT, leucine rich repeat and PYD containing 8; NACHT, LRR and PYD containing protein 8; NACHT, LRR and PYD domains-containing protein 8; NALP8; NLR family pyrin domain containing 8; NLR family, pyrin domain containing 8; NLRP8; NOD16; Nucleotide-binding oligomerization domain protein 16; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 8; PAN4; PYRIN and NACHT-containing protein 4
Gene Symbols NLRP8
Host Species Rabbit
Immunogen A 16 amino acid peptide near the amino terminus of human NALP8.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 126205
Target Species Human
Content And Storage Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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