NALP1 Monoclonal Antibody (Nalpy1-4), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen MA125842

Product Code. 11539382

Description

MA1-25842 detects NALP1 from human samples. MA1-25842 has been successfully used in immunocytochemistry, immunohistochemistry (frozen), immunohistochemistry (paraffin), immunoprecipitation, immunofluorescence and Western blot procedures. The MA1-25842 immunogen is recombit, full length human NALP1 (pyrin domain).

This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.

Specifications

• Antigen: NALP1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Gene: NLRP1
• Gene Alias: CARD7, CLR17.1, DEFCAP, DEFCAP-L/S, DKFZp586O1822, KIAA0926, NAC, NALP1, PP1044, SLEV1, VAMAS1
• Host Species: Mouse
• Purification Method: Igg Fraction
• Regulatory Status: RUO
• Gene ID (Entrez): 22861
• Content And Storage: 4° C
• Form: Liquid

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Clone: Nalpy1-4
• Conjugate: Unconjugated
• Gene Accession No.: Q9C000
• Gene Symbols: NLRP1
• Immunogen: Recombit, full length human NALP1 (pyrin domain).
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1