Invitrogen™ Naja kaouthia Cobra Venom Factor Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5117705

Product Code. 17240204

Description

This antibody has been tested in direct-ELISA.

Complement-activating protein in cobra venom. It is a structural and functional analog of complement component C3b, the activated form of C3. It binds factor B (CFB), which is subsequently cleaved by factor D (CFD) to form the bimolecular complex CVF/Bb. CVF/Bb is a C3/C5 convertase that cleaves both complement components C3 and C5. Structurally, it resembles the C3b degradation product C3c, which is not able to form a C3/C5 convertase. Unlike C3b/Bb, CVF/Bb is a stable complex and completely resistant to the actions of complement regulatory factors H (CFH) and I (CFI). Therefore, CVF continuously activates complement resulting in the depletion of complement activity.

Specifications

• Antigen: Naja kaouthia Cobra Venom Factor
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Alias: CVF
• Immunogen: Recombinant Naja kaouthia Cobra venom factor protein (733-984aa).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: Western Blot
• Concentration: 5 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Target Species: Reptile
• Product Type: Antibody
• Isotype: IgG