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Invitrogen™ N4BP1 Polyclonal Antibody

Product Code. 12859242
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Quantity:
100 μg
Unit Size:
100µg
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Product Code. Quantity unitSize
12859242 100 μg 100µg
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Product Code. 12859242 Supplier Invitrogen™ Supplier No. PA521099

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Description

Rabbit Polyclonal Antibody

A suggested positive control is Hela cell lysate. PA5-21099 can be used with blocking peptide PEP-1213.

Nedd4-binding partner-1 (N4BP1) is a developmentally expressed protein interactor and monoubiquitylation substrate of Nedd4, a HECT domain-containing ubiquitin ligase that mediates ubiquitylation and proteasome degradation of target proteins and may have a fundamental role to play in embryonic processes. N4BP1 can undergo Nedd4-mediated polyubiquitylation and proteosomal degradation. N4BP1 also functions as a negative regulator of AIF4 (also known as ITCH or Atrophin-1), an E3-ubiquitin ligase, by interacting with the second WW domain of AIF4 and impairing ubiquitination of substrates.
TRUSTED_SUSTAINABILITY

Specifications

Antigen N4BP1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene N4BP1
Gene Accession No. O75113, Q6A037
Gene Alias AI481586; C81621; Kiaa0615; N4BP1; Nedd4 binding protein 1; NEDD4-binding protein 1; RGD1305179
Gene Symbols N4BP1
Host Species Rabbit
Immunogen An 18 amino acid peptide near the amino terminus of human N4BP1.
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 291921, 80750, 9683
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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