N,O-Bis(trimethylsilyl)trifluoroacetamide, with 1% TMCS, packaged under Argon in resealable ChemSeal™ bottles

Product Code.	Quantity	unitSize
11394978	25 g	25g
11384978	5 g	5g

Product Code. 11394978

Brand: Thermo Scientific Alfa Aesar 043928.14

Description

CAS: 25561-30-2 | C8H18F3NOSi2 | 257.403 g/mol

N,O-Bis(trimethylsilyl)trifluoroacetamide is used for analytical purposes or as a chemical reagent for synthesis of more complex molecules. It is silylation reagent useful in GC and GC-MS for the derivatization of a wide range of functional groups under mild conditions. It is also used as DAT inhibitor and a SLC6A2 inhibitor. It is routinely used to derivatize carboxylic acids, phenols, steroids, amines, alcohols, and alkaloids and amides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

• Packaged under Argon

Specifications

Chemical Identifiers

• CAS: 25561-30-2
• Molecular Formula: C8H18F3NOSi2
• Molecular Weight (g/mol): 257.403
• MDL Number: MFCD00008269
• InChI Key: XCOBLONWWXQEBS-GHXNOFRVSA-N
• Synonym: bstfa, n,o-bis trimethylsilyl trifluoroacetamide, acetamide, 2,2,2-trifluoro-o,n-bis trimethylsilyl, trimethylsilyl 2,2,2-trifluoro-n-trimethylsilyl acetimidate, trimethylsilyl 2,2,2-trifluoro-n-trimethylsilyl ethanimidate, trimethylsilyl 1z-2,2,2-trifluoro-n-z-trimethylsilyl ethanimidoate #, n,o-bis trimethylsilyl trifluoroacetamide bstfa, trimethylsilyl 2,2,2-trifluoro-n-trimethylsilyl ethanecarboximidate
• PubChem CID: 9601896
• IUPAC Name: trimethylsilyl (1Z)-2,2,2-trifluoro-N-trimethylsilylethanimidate
• SMILES: C[Si](C)(C)N=C(C(F)(F)F)O[Si](C)(C)C

• Melting Point: -10°C
• Color: Colorless to Yellow
• Density: 0.97 g/mL
• Boiling Point: 145°C to 147°C
• Flash Point: 23°C (73°F)
• Packaging: ChemSeal™ bottles
• Refractive Index: 1.384
• Quantity: 25 g
• UN Number: UN2924
• Beilstein: 3607620
• Sensitivity: Moisture sensitive
• Solubility Information: Soluble in water (hydrolyses),chloroform and hexane.
• Formula Weight: 257.4
• Physical Form: Liquid
• Chemical Name or Material: N,O-Bis (trimethylsilyl)trifluoroacetamide, With 1% TMCS

Safety and Handling

Product Identifier

• N,O-Bis(trimethylsilyl)trifluoroacetamide, with 1% TMCS, packaged under Argon in resealable ChemSeal bottles

Signal Word

• Warning

Hazard Category

• Serious eye damage/eye irritation Category 2
• Flammable liquid Category 3
• Skin corrosion/irritation Category 2

Hazard Statement

• H226-Flammable liquid and vapour.
• H315-Causes skin irritation.
• H319-Causes serious eye irritation.
• EUH014-Reacts violently with water.

Precautionary Statement

• P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P332+P313-If skin irritation occurs: Get medical advice/attention.
• P337+P313-If eye irritation persists: Get medical advice/attention.

Supplemental information

• MIXTURE LIST-Contains : N,O-Bis(trimethylsilyl)trifluoroacetamide

SDS

RUO – Research Use Only