Invitrogen™ n-Myc Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5105270

Product Code. 16651715

Description

Antibody detects endogenous levels of total n-Myc.

N-Myc protein is member of the MYC family of transcription factor proteins with a basic helix-loop-helix (bHLH) domain. N-Myc is similarly regulated and functionally complementary to C-Myc in the context of various cellular growth and differentiation processes. MYCN gene is considered the hallmark of neuroblastoma, amplification and overexpression of the MYCN proto-oncogene occurs in approximately 20% of neuroblastomas and is associated with advanced stage disease, rapid tumor progression, and poor prognosis.

Specifications

• Antigen: n-Myc
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MYCN
• Gene Alias: Avian myelocytomatosis viral (v-myc) related oncogene neuroblastoma derived (Nmyc); Avian myelocytomatosis viral (v-myc) related oncogene, neuroblastoma derived (Nmyc); BHLHE37; Class E basic helix-loop-helix protein 37; c-nmyc; fb57a02; MODED; Mycn; mycn protein; MYCN proto-oncogene, bHLH transcription factor; neuroblastoma MYC oncogene; neuroblastoma myc-related oncogene 1; neuroblastoma-derived v-myc avian myelocytomatosis viral related oncogene; Nmuc1; NMYC; N-myc; N-myc protein; N-myc proto-oncogene protein; Nmyc1; Nmyc-1; N-myc-like protein; ODED; oncogene NMYC; oncogene pp65/67; pp65/67; v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog; v-myc myelocytomatosis viral related oncogene, neuroblastoma derived; v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian); wu:fb57a02; zgc:85706
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18109, 298894, 4613
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P03966, P04198, Q63379
• Gene Symbols: MYCN
• Immunogen: A synthesized peptide derived from human MYCN(Accession P04198), corresponding to amino acid residues A235-R285.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG