N-Hydroxysuccinimide, 98+%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11494063	Thermo Scientific Alfa Aesar A10312.14	25 g
11404073	Thermo Scientific Alfa Aesar A10312.22	100 g
11414073	Thermo Scientific Alfa Aesar A10312.36	500 g

Description

N-Hydroxysuccinimide is used for improved amidations in the carbodiimide method. It is also used to activate a carboxyl group and reacts with amine to form amide. It is involved in the preparation of N-hydroxymaleimide-styrene copolymer. Further, it finds use in analytical chemistry. As an additive, it is used in the carbodiimide method for improved amidations and peptide couplings.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
N-Hydroxysuccinimide is used for improved amidations in the carbodiimide method. It is also used to activate a carboxyl group and reacts with amine to form amide. It is involved in the preparation of N-hydroxymaleimide-styrene copolymer. Further, it finds use in analytical chemistry. As an additive, it is used in the carbodiimide method for improved amidations and peptide couplings.

Solubility
Soluble in water, dimethyl formamide, alcohols and ethyl acetate. Insoluble in cold ether.

Notes
Hygroscopic. Moisture sensitive. Incompatible with strong oxidizing agents, acid chlorides, acid anhydrides and strong bases. Store in a cool place.

Chemical Identifiers

• CAS: 6066-82-6
• Molecular Weight (g/mol): 115.088
• InChI Key: NQTADLQHYWFPDB-UHFFFAOYSA-N
• PubChem CID: 80170
• SMILES: C1CC(=O)N(C1=O)O

• Molecular Formula: C4H5NO3
• MDL Number: MFCD00005516
• Synonym: n-hydroxysuccinimide, hosu, 1-hydroxysuccinimide, 2,5-pyrrolidinedione, 1-hydroxy, 1-hydroxy-2,5-pyrrolidinedione, succinimide, n-hydroxy, n-hydroxysuccinimde, n-hydroxysuccinimid, unii-mje3791m4t, ccris 2604
• IUPAC Name: 1-hydroxypyrrolidine-2,5-dione

Specifications

• CAS: 6066-82-6
• Assay Percent Range: >98%
• MDL Number: MFCD00005516
• Sensitivity: Hygroscopic
• Solubility Information: Soluble in water,dimethyl formamide,alcohols and ethyl acetate. Insoluble in cold ether.
• SMILES: C1CC(=O)N(C1=O)O
• Molecular Weight (g/mol): 115.088
• Formula Weight: 115.09
• Chemical Name or Material: N-Hydroxysuccinimide

• Melting Point: 94°C to 99°C
• Molecular Formula: C4H5NO3
• Beilstein: 113913
• Synonym: n-hydroxysuccinimide, hosu, 1-hydroxysuccinimide, 2,5-pyrrolidinedione, 1-hydroxy, 1-hydroxy-2,5-pyrrolidinedione, succinimide, n-hydroxy, n-hydroxysuccinimde, n-hydroxysuccinimid, unii-mje3791m4t, ccris 2604
• InChI Key: NQTADLQHYWFPDB-UHFFFAOYSA-N
• IUPAC Name: 1-hydroxypyrrolidine-2,5-dione
• PubChem CID: 80170
• Percent Purity: ≥98%

Safety and Handling

P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c

H315-H319-H335

missing translation for 'einecsNumber' : 228-001-3

missing translation for 'tsca' : Yes

Recommended Storage : Ambient temperatures

RUO – Research Use Only