N-Ethylmaleimide, 98+%

Codice prodotto.	Quantity	unitSize
11330014	10 g	10g
11340014	50 g	50g

Codice prodotto. 11330014 Fornitore Thermo Scientific Alfa Aesar N. del fornitore L00355.09

Descrizione

CAS: 128-53-0 | C6H7NO2 | 125.127 g/mol

Cysteine alkylating agent N-Ethylmaleimide is a protein thiol modifier which inhibits apoptotic DNA fragmentation. It is a sulfhydryl reagent and finds application in experimental biochemical studies as well as in enzymology. It is involved in the modification of cysteine residues in proteins and peptides. It acts as a Michael acceptor and reacts with nucelophiles like thiols. It is employed in the inhibition of Mg²⁺-dependent internucleosomal DNA fragmentation.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Cysteine alkylating agent N-Ethylmaleimide is a protein thiol modifier which inhibits apoptotic DNA fragmentation. It is a sulfhydryl reagent and finds application in experimental biochemical studies as well as in enzymology. It is involved in the modification of cysteine residues in proteins and peptides. It acts as a Michael acceptor and reacts with nucelophiles like thiols. It is employed in the inhibition of Mg²⁺-dependent internucleosomal DNA fragmentation.

Solubility
Soluble in ethanol, water, chloroform, methanol and toluene.

Notes
Light sensitive. Store in cool place. Incompatible with strong oxidizing agents, strong acids and strong bases.

Specifica

Identificatori chimici

• CAS: 128-53-0
• Molecular Formula: C6H7NO2
• Molecular Weight (g/mol): 125.127
• MDL Number: MFCD00005509
• InChI Key: HDFGOPSGAURCEO-UHFFFAOYSA-N
• Synonym: n-ethylmaleimide, ethylmaleimide, 1-ethyl-1h-pyrrole-2,5-dione, maleimide, n-ethyl, 1h-pyrrole-2,5-dione, 1-ethyl, maleic acid n-ethylimide, nem, usaf b-121, unii-o3c74acm9v, maleic acid-n-ethylimide
• PubChem CID: 4362
• ChEBI: CHEBI:44485
• IUPAC Name: 1-ethylpyrrole-2,5-dione
• SMILES: CCN1C(=O)C=CC1=O

• Melting Point: 43°C to 46°C
• Boiling Point: 209°C to 211°C
• Flash Point: 73°C (163°F)
• Odor: Pungent
• Quantity: 10 g
• UN Number: UN2928
• Beilstein: 112448
• Sensitivity: Light sensitive
• Merck Index: 14,3822
• Solubility Information: Soluble in ethanol,water,chloroform,methanol and toluene.
• Formula Weight: 125.13
• Percent Purity: ≥98%
• Chemical Name or Material: N-Ethylmaleimide

Sicurezza e movimentazione

Identificativo prodotto

• N-Ethylmaleimide

Avvertenza

• Danger

Categoria di pericolo

• Acute toxicity Category 2
• Skin corrosion/irritation Category 1 B
• Acute toxicity Category 4
• Skin sensitiser Category 1

Indicazioni di pericolo

• H300-Fatal if swallowed.
• H312-Harmful in contact with skin.
• H314-Causes severe skin burns and eye damage.
• H317-May cause an allergic skin reaction.

Consigli di prudenza

• P260-Do not breathe dust/fume/gas/mist/vapours/spray.
• P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
• P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P405-Store locked up.
• P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.

SDS

RUO – Research Use Only