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Invitrogen™ MYZAP Polyclonal Antibody

Product Code. 12819262
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Quantity:
100 μg
Unit Size:
100µg
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12819262 100 μg 100µg
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Product Code. 12819262 Supplier Invitrogen™ Supplier No. PA521116

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Description

Rabbit Polyclonal Antibody

A suggested positive control is rat kidney tissue lysate. PA5-21116 can be used with blocking peptide PEP-1230.

MYOZAP, also known as GRINL1A, is a 54 kDa highly conserved cardiac protein. It is strongly expressed in the heart and lung and is a novel component of intercalated disc. MYOZAP interacts with myosin phosphatase-RhoA interacting protein (MRIP) and acts as an activator of Rho-dependent SRF signaling. Knockdown study in zebrafish results in cardiomyopathy with severe dysfunction. The MYOZAP gene is part of a complex transcript unit that includes the gene for glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A (GRINL1A). Transcription of this gene occurs at an upstream promoter, with two different groups of alternatively spliced variants: Gup for GRINL1A upstream transcripts and Gcom for GRINL1A combined transcripts.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MYZAP
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene MYZAP
Gene Accession No. P0CAP1, Q3UIJ9, Q5EB94
Gene Alias AA407270; AV006038; gcom; GCOM1; Gcom2; Gm640; GRINL1A; GRINL1A combined protein; GRINL1A complex locus 1; GRINL1A complex locus protein 1; GRINL1A complex locus upstream; GRINL1A upstream protein; Grinl1a7; Gup; myocardial intercalated disc protein; myocardial zonula adherens protein; myocardium-enriched ZO1-associated protein; myocardium-enriched zonula adherens protein; myocardium-enriched zonula occludens-1-associated protein; myozap; Myzap; MYZAP-POLR2M
Gene Symbols MYZAP
Host Species Rabbit
Immunogen An 18 amino acid peptide near the carboxy terminus of human MYOZAP.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100820829, 102371, 363091
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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