Invitrogen™ MYSM1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA584747

Product Code. 16371695

Description

Immunogen sequence: VNCIGRIHTY LELIGAINFG CEQAVYNRPQ TVDKVRIRDR KDAVEAYQLA QRLQSMRTRR RRVRDPWGNW CDAKDLEGQT FEHLS Highest antigen sequence indentity to the following orthologs: Mouse - 92%, Rat - 92%.

Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.

Specifications

• Antigen: MYSM1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Mysm1
• Gene Alias: 2ADUB; 2A-DUB; C130067A03Rik; C530050H10Rik; Histone H2A deubiquitinase MYSM1; KIAA1915; Myb like, SWIRM and MPN domains 1; myb-like, SWIRM and MPN domain-containing protein 1; myb-like, SWIRM and MPN domains 1; Mysm1; RGD1311787; RP4-592A1.1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 114803
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q5VVJ2
• Gene Symbols: Mysm1
• Immunogen: Recombinant protein corresponding to Human MYSM1. Recombinant protein control fragment (Product #RP-105418).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG