Invitrogen™ MYO5A Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5110003

Product Code. 17157933

Description

Immunogen sequence: LTNLEGIYNS ETEKLRSDLE RLQLSEEEAK VATGRVLSLQ EEIAKLRKDL EQTRSEKKCI EEHADRYKQE TEQLVSNLKE ENTLLKQEKE ALNHRIVQQA KEMTETMEKK LVEETKQLEL DLNDERLRYQ NLLNEFSRLE ERYDDLKEEM TLMVHVPKPG HKRTDSTHSS NESEYIFSSE IAEMEDIPSR TEEPSEKKVP L.

This gene is one of three myosin V heavy-chain genes, belonging to the myosin gene superfamily. Myosin V is a class of actin-based motor proteins involved in cytoplasmic vesicle transport and anchorage, spindle-pole alignment and mRNA translocation. The protein encoded by this gene is abundant in melanocytes and nerve cells. Mutations in this gene cause Griscelli syndrome type-1 (GS1), Griscelli syndrome type-3 (GS3) and neuroectodermal melanolysosomal disease, or Elejalde disease. Multiple alternatively spliced transcript variants encoding different isoforms have been reported, but the full-length nature of some variants has not been determined.

Specifications

• Antigen: MYO5A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MYO5A
• Gene Alias: 9630007J19Rik; AI413174; AI661011; D; d-120J; Dbv; Dilute; dilute lethal-20J protein; dilute myosin heavy chain, non-muscle; dilute-opisthotonus; Dop; flail; flailer; flr; GS1; MVa; MYH12; MYO5; Myo5a; myosin 5a; Myosin heavy chain 12; Myosin heavy chain p190; myosin I heavy chain isoform; myosin V; myosin VA; myosin VA (heavy chain 12, myosin); myosin VA (heavy chain 12, myoxin); myosin VA (heavy polypeptide 12, myoxin); myosin, heavy polypeptide kinase; myosin-12; Myosin-V; myosin-Va; MyoVA; myoxin; MYR12; OTTMUSP00000017756; OTTMUSP00000019176; OTTMUSP00000046608; p190 myosin heavy chain; Sev-1; unconventional myosin-Va
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 17918, 25017, 4644
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.86 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q99104, Q9QYF3, Q9Y4I1
• Gene Symbols: MYO5A
• Immunogen: Recombinant protein (or fragment).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG