Invitrogen™ Human MYO3A (MYO3 alpha), GST Tag Recombinant Protein

Product Code. 15990303

Brand: Invitrogen™ A30981

Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. This MYO3A (MYO3 alpha) recombinant human protein (1-434) was expressed in insect cells. MYO3A (MYO3 alpha) recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service. Validated for use with the LanthaScreen™ Eu Kinase Binding assay Available in multiple pack sizes for convenient use Also available in our SelectScreen Kinase Profiling Service Protein Form: Recombinant, Active, Catalytic The gene accession number for MYO3A (MYO3 alpha) is NP_059129.3.

MYO3A (MYO3 alpha) serine/threonine kinase belongs to the myosin superfamily where they are categorized into conventional myosins (class II) and unconventional myosins (classes I and III through XV) based on their variable C-terminal cargo-binding domains. Class III myosins, such as MYO3A, have a kinase domain N-terminal to the conserved N-terminal motor domains and are expressed in photoreceptors. MYO3A plays an important role in hearing in humans and mutations in the MYO3A have been shown to cause nonsyndromic progressive hearing loss. MYO3A is highly expressed in retina and cochlea.

Specifications

• Accession Number: Q8NEV4
• Concentration: See Label
• For Use With (Application): Kinase Assay
• Formulation: 50mM tris HCl with 0.25mM DTT, 0.1mM PMSF, 0.1mM EDTA, 10mM glutathione, 150mM NaCl, 25% glycerol and no preservative; pH 7.5
• Gene ID (Entrez): 53904
• Molecular Weight (g/mol): 75.3 kDa
• Name: Human MYO3A (MYO3 alpha), GST Tag
• pH Range: 7.5
• Purification Method: Purified
• Quantity: 10 μg
• Storage Requirements: -80°C, Avoid Freeze/Thaw Cycles
• Regulatory Status: RUO
• Gene Alias: DFNB30; MYO3A; myosin IIIA; myosin-IIIa
• Common Name: MYO3A
• Gene Symbol: MYO3A
• KinaseFamily: STE20 Kinase Family
• Protein Length: 1-434
• Product Type: Protein
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: GST-tag
• Sequence: 1-434
• Content And Storage: -80°C, Avoid Freeze/Thaw Cycles
• Shipping Condition: Dry Ice
• Expression System: Insect cells
• Protein Family: Kinases & Inhibitors
• Protein Form: Recombinant, Active, Catalytic
• Form: Liquid