MYO18A Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA554328

Product Code. 15752261

Description

Immunogen sequence: RFSFSQRSRD ESASETSTPS EHSAAPSPQV EVRTLEGQLV QHPGPGIPRP GHRSRAPELV TKKFPVDLRL PPVVPLPPPT LRELELQRRP TGDFGFSLRR TTMLDRGPEG QACRRVVHFA EP Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 89%.

MYO18A may link Golgi membranes to the cytoskeleton and participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus. Alternatively, in concert with LURAP1 and CDC42BPA/CDC42BPB, has been involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. May be involved in the maintenance of the stromal cell architectures required for cell to cell contact. Regulates trafficking, expression, and activation of innate immune receptors on macrophages. Plays a role to suppress inflammatory responsiveness of macrophages via a mechanism that modulates CD14 trafficking.

Specifications

• Antigen: MYO18A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MYO18A
• Gene Alias: CD245; KIAA0216; MAJN; molecule associated with JAK3 N-terminus; Myo18a; MyoPDZ; myosin 18a; myosin containing a PDZ domain; myosin containing PDZ domain; myosin XVIIIa; myosin XVIIIb; myosin-XVIIIa; MysPDZ; SP-A receptor subunit SP-R210 alphaS; SPR210; SP-R210; Surfactant protein receptor SP-R210; Unconventional myosin-XVIIIa
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 399687
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry
• Concentration: 0.4 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q92614
• Gene Symbols: MYO18A
• Immunogen: Recombinant protein corresponding to Human MYO18A
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Research Use Only