Invitrogen™ MYL2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA596334

Product Code. 16579171

Description

Immunogen sequence: MAPKKAKKRA GGANSNVFSM FEQTQIQEFK EAFTIMDQNR DGFIDKNDLR DTFAALGRVN VKNEEIDEMI KEAPGPINFT VFLTMFGEKL KGADPEETIL NAFKVFDPEG KGVLKADYVR EMLTTQAERF SKEEVDQMFA AFPPDVTGNL DYKNLVHIIT HGEEKD; Positive Samples: MCF7, Mouse skeletal muscle; Cellular Location: A band, Cytoplasm, myofibril, sarcomere.

Thus gene encodes the regulatory light chain associated with cardiac myosin beta heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in this gene are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.

Specifications

• Antigen: MYL2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MYL2
• Gene Alias: cardiac myosin light chain 2; cardiac myosin light chain-2; cardiac ventricular myosin light chain 2; CMH10; DKFZp779C0562; hypothetical protein LOC677750; Mlc2; MLC-2; mlc2b; MLC-2s/v; MLC2V; MLC-2v; myl2; myl2b; Mylpc; myosin light chain 2; myosin light chain 2, slow skeletal/ventricular muscle isoform; myosin light chain 2V; myosin light chain phosphatase; myosin light chain, phosphorylatable, cardiac ventricles; myosin light chain-2; myosin regulatory light chain 2, ventricular/cardiac muscle isoform; myosin regulatory light chain 2b; myosin regulatory light chain ventricular isoform; myosin, light chain 2, regulatory, cardiac, slow; myosin, light chain 2b, regulatory, cardiac, slow; myosin, light polypeptide 2, regulatory, cardiac, slow; myosin, light polypeptide 2b, regulatory, cardiac, slow; regulatory light chain of myosin; RLC of myosin; slow cardiac myosin regulatory light chain 2; ventricular myosin light chain 2; ventricular myosin regulatory light chain; zgc:136848
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 17906, 363925, 4633
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.54 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P08733, P10916, P51667
• Gene Symbols: MYL2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-166 of human MYL2 (NP_0004232).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG