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Invitrogen™ MYF5 Polyclonal Antibody
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Product Code. 17208393 Shop All Thermo Scientific Products
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Quantity:
100 μL
Unit Size:
100µL
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17208393 100 μL 100µL
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Product Code. 17208393 Supplier Invitrogen™ Supplier No. PA5115608

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total MYF5.

Myogenic factor 5 (MYF5) is a gene located on chromosome 12q21.31, encoding a basic helix-loop-helix (bHLH) transcription factor essential for skeletal muscle development and differentiation. MYF5 is one of the key members of the myogenic regulatory factor (MRF) family, which also includes MyoD, myogenin, and MRF4. It plays a crucial role in myogenesis by regulating the expression of genes necessary for muscle precursor cell proliferation and differentiation into mature muscle fibers. During embryonic development, MYF5 is involved in the formation of muscle tissue and maintenance of muscle progenitor cells. Mutations or dysregulation in MYF5 can lead to developmental abnormalities in muscle formation and are implicated in muscle-related disorders. Research into MYF5 continues to explore its regulatory mechanisms in muscle biology and potential therapeutic applications in muscular dystrophies and muscle repair processes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MYF5
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene MYF5
Gene Accession No. P13349, P24699
Gene Alias B130010J22Rik; basic helix-loop-helix nuclear protein; bHLHc2; cb641; Class C basic helix-loop-helix protein 2; muscle regulatory protein Myf5; MYF5; myf-5; myf5 protein; MyoD family; myogenic factor 5; myogenic factor-5; myogenic regulatory factor 5; myogenic regulatory factor MYF-5; unnamed protein product; zgc:110509
Gene Symbols MYF5
Host Species Rabbit
Immunogen A synthesized peptide derived from human MYF5(Accession P13349), corresponding to amino acid residues E25-C75.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17877, 299766, 4617
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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