MYDGF Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 11353-1-AP-20UL

Product Code. 16808373

Description

The interleukins are a broad family of well characterized cytokines, primarily of hematopoietic cell origin. Cytokines are small, soluble proteins with pleiotropic effects on a variety of cell types. Cytokines have a regulatory function over the immune system and mediate aspects of inflammatory response. IL-25 (also called SF20/IL-25) is a secreted bone marrow stroma-derived growth factor cytokine that is derived from Th2 T-cells. IL-25 belongs to the IL-17 cytokine family and is capable of amplifying allergic type inflammatory responses by its actions on other cell types. IL-25 binds to mouse thymic shared antigen-1 and supports lymphoid cell proliferation. Infusion of mice with IL-25 induces IL-4, IL-5, and IL-13 gene expression. IL-25 induced mice also develop epithelial cell hyperplasia, increased mucus secretion, and airway hyperreactivity, suggesting that IL-25 may be an important mediator of allergic disease via production of IL-4, IL-5, IL-13 and eotaxin.

Specifications

• Antigen: MYDGF
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MYDGF
• Gene Alias: C19orf10, MYDGF, Myeloid-derived growth factor, SF20
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 28106, 56005
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry, Western Blot, Immunofluorescence
• Concentration: 0.19 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: Q969H8, Q9CPT4
• Gene Symbols: Mydgf
• Immunogen: MYDGF Fusion Protein Ag1900
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Human
• Product Type: Antibody
• Isotype: IgG