Invitrogen™ MyD88 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA529611

Product Code. 13483797

Description

Recommended positive controls: MyD88-transfected 293T. Predicted reactivity: Mouse (82%), Rat (81%), Pig (86%), Sheep (83%), Rhesus Monkey (99%), Chimpanzee (99%), Bovine (84%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Myeloid differentiation Marker 88 (MyD88) is an adaptor molecule for the Toll/IL-1R and is involved in the inflammatory response induced by IL-1, IL-18 and LPS. MyD88 recruits IRAK to IL-1 receptor complex in response to IL-1. This pathway further leads to activation of NF-kB. MyD88 has a wide tissue distribution.

Specifications

• Antigen: MyD88
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MYD88
• Gene Alias: mutant myeloid differentiation primary response 88; Myd88; MYD88D; myeloid differentiation primary response 88; myeloid differentiation primary response gene (88); myeloid differentiation primary response gene 88; myeloid differentiation primary response protein MyD88
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 17874, 4615
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1.18 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: P22366, Q99836
• Gene Symbols: MYD88
• Immunogen: Recombinant protein encompassing a sequence within the center region of human MYD88. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG