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Invitrogen™ MyD88 Polyclonal Antibody

Product Code. 12858132
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Quantity:
100 μg
Unit Size:
100µg
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12858132 100 μg 100µg
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Product Code. 12858132 Supplier Invitrogen™ Supplier No. PA519918

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Description

Rabbit Polyclonal Antibody

A suggested positive control is Jurkat cell lysate. PA5-19918 can be used with blocking peptide PEP-0044. The PA5-19918 The immunogen is located within amino acids 220 - 270 of MYD88. Predicted molecular ~ 35kD. In Western blot applications, this antibody has been observed to detect a band at: 35kD Predicted species reactivity based on immunogen sequence: Pig: (100%), Sheep: (100%), Bovine: (100%), Chicken: (100%), Rat: (88%), Mouse (88%).

Myeloid differentiation Marker 88 (MyD88) is an adaptor molecule for the Toll/IL-1R and is involved in the inflammatory response induced by IL-1, IL-18 and LPS. MyD88 recruits IRAK to IL-1 receptor complex in response to IL-1. This pathway further leads to activation of NF-kB. MyD88 has a wide tissue distribution.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MyD88
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene MYD88
Gene Accession No. P22366, Q6Y1S1, Q99836
Gene Alias mutant myeloid differentiation primary response 88; Myd88; MYD88D; myeloid differentiation primary response 88; myeloid differentiation primary response gene (88); myeloid differentiation primary response gene 88; myeloid differentiation primary response protein MyD88
Gene Symbols MYD88
Host Species Rabbit
Immunogen A 16 amino acid peptide near the center of human MYD88 isoform 1.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17874, 301059, 4615
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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