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Invitrogen™ MyD88 Polyclonal Antibody

Product Code. 12848132
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Quantity:
100 μg
Unit Size:
100µg
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12848132 100 μg 100µg
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Product Code. 12848132 Supplier Invitrogen™ Supplier No. PA519919

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Rabbit Polyclonal Antibody

Suggested positive controls are A431, A549, K562, HepG2, or NIH/3T3 Cell Lysates. PA5-19919 can be used with blocking peptide PEP-0045. Predicted molecular ~ 35kD. In Western blot applications, this antibody has been observed to detect a band at: 35kD Predicted species reactivity based on immunogen sequence: Pig: (94%), Sheep: (82%), Bovine: (82%), Chicken: (82%) Antibodies should not be exposed to prolonged high temperatures.

Myeloid differentiation Marker 88 (MyD88) is an adaptor molecule for the Toll/IL-1R and is involved in the inflammatory response induced by IL-1, IL-18 and LPS. MyD88 recruits IRAK to IL-1 receptor complex in response to IL-1. This pathway further leads to activation of NF-kB. MyD88 has a wide tissue distribution.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MyD88
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene MYD88
Gene Accession No. P22366, Q6Y1S1, Q99836
Gene Alias mutant myeloid differentiation primary response 88; Myd88; MYD88D; myeloid differentiation primary response 88; myeloid differentiation primary response gene (88); myeloid differentiation primary response gene 88; myeloid differentiation primary response protein MyD88
Gene Symbols MYD88
Host Species Rabbit
Immunogen A peptide corresponding to 17 amino acids near carboxy terminus of human MYD88 isoform 1. The immunogen is located within the last 50 amino acids of MYD88.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17874, 301059, 4615
Target Species Human, Mouse, Rat
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG
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