Myc Tag Monoclonal Antibody (Myc.A7), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen MA121316

Product Code. 11543923

Description

MA1-21316 detects N-terminal or C-terminal Myc tagged fusion proteins. MA1-21316 may be stored at 4° C short term. Add 0.05% sodium azide if desired. For long term storage, store at -20° C, avoiding freeze/thaw cycles.

Myc is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini.

Specifications

• Antigen: Myc Tag
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative; pH 7.2
• Gene Accession No.: P01106
• Gene Symbols: MYC
• Immunogen: Synthetic peptide: EQKLISEEDL (Myc).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid
• Target Molecule: Tag

• Applications: ChIP Assay, ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot
• Clone: Myc.A7
• Conjugate: Unconjugated
• Gene: MYC
• Gene Alias: 46-0603; AU016757; avian myelocytomatosis viral oncogene homolog; bHLHe39; c Myc; class E basic helix-loop-helix protein 39; cmyc; c-Myc; c-myc epitope tag; c-myc proto-oncogene; MRTL; MYC; Myc protein; Myc proto-oncogene protein; Myc Tag; Myc2; MYCC; myc-related translation/localization regulatory factor; myelocytomatosis oncogene; Niard; Nird; Proto-oncogene c-Myc; R95025; R950-25; transcription factor p64; v-myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 4609
• Product Type: Antibody
• Isotype: IgG1