Invitrogen™ MYBPC2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA589164

Product Code. 16577161

Description

Immunogen sequence: LSVQIENMKD TATIRIRVVE KAGPPINVMV KEVWGTNALV EWQAPKDDGN SEIMGYFVQK ADKKTMEWFN VYERNRHTSC TVSDLIVGNE YYFRVYTENI CGLSDSPGVS KNTARILKTG ITFKPFEYKE HDFRMAPKFL TPLIDRVVVA GYSAALNCAV RGHPKPKVVW MKNKMEIRED PKFLITNYQG VLTLNIRRPS PFDAGTYTCR AVNELGEALA ECKLEVRVPQ; Positive Samples: Mouse skeletal muscle, Rat skeletal muscle.

The gene MYBPC2 belongs to the myosin-binding protein C family, which consists of fast-, slow-, and cardiac-type isoforms. These isoforms are myosin-associated proteins that are located in the C region of A bands in striated muscle. The protein encoded by MYBPC2 is the fast-type isoform. Mutations in genes encoding the slow-type and cardiac-type isoforms have been linked to distal arthrogryposis, type 1, and hypertrophic cardiomyopathy, respectively. MYBPC2-related diseases include Lethal Congenital Contracture Syndrome 4 and Nemaline Myopathy 9.

Specifications

• Antigen: MYBPC2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MYBPC2
• Gene Alias: C-protein, skeletal muscle fast isoform; Fast MyBP-C; fast-type C-protein; fast-type muscle myosin-binding-protein C; MYBPC; Mybpc2; MYBPCF; myosin binding protein C, fast type; myosin binding protein C, fast-type; myosin-binding protein C, fast-type; mypc2; testicular tissue protein Li 126
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 233199, 292879, 4606
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.82 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q14324, Q5XKE0
• Gene Symbols: MYBPC2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 912-1141 of human MYBPC2 (NP_0045243).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG