Invitrogen™ MUT Monoclonal Antibody (2D6)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA549182

Product Code. 17931491

Description

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL. Immunogen sequence is different from the related mouse sequence by one amino acid. Positive Control - WB: human Hela whole cell, human K562 whole cell, human HEK293 whole cell, human PC-3 whole cell, human Caco-2 whole cell, human Raji whole cell, rat PC-12 whole cell, mouse NIH/3T3 whole cell. IHC: human mammary cancer tissue, human rectal cancer tissue, human rectal cancer tissue, rat intestine tissue. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

The product of this gene is a Golgi enzyme catalyzing an essential step in the conversion of oligomannose to complex N-glycans. The enzyme has the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain, and a C-terminal catalytic domain. Mutations in this gene may lead to carbohydrate-deficient glycoprotein syndrome, type II. The coding region of this gene is intronless. Transcript variants with a spliced 5' UTR may exist, but their biological validity has not been determined.

Specifications

• Antigen: MUT
• Classification: Monoclonal
• Concentration: 500 μg/mL
• Formulation: PBS with 4mg trehalose and 0.05mg sodium azide
• Gene Accession No.: P16332, P22033
• Gene Symbols: MMUT
• Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human MUT (33-65aa LHQQQPLHPEWAALAKKQLKGKNPEDLIWHTPE).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: 2D6
• Conjugate: Unconjugated
• Gene: MMUT
• Gene Alias: D230010K02Rik; Mcm; methylmalonyl CoA mutase; methylmalonyl Coenzyme A mutase; methylmalonyl-CoA isomerase; methylmalonyl-CoA mutase; methylmalonyl-CoA mutase, mitochondrial; methylmalonyl-Coenzyme A mutase; MMUT; MUT; mutant methylmalonyl CoA mutase; truncated methylmalonyl CoA mutase
• Host Species: Mouse
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 17850, 4594, 688517
• Content And Storage: -20°C
• Form: Lyophilized