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Invitrogen™ MUSK Biosimilar Recombinant Monoclonal Antibody

Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA559031
Description
For reconstitution, add sterile, distilled water to achieve a final antibody concentration of 1 mg/mL. Gently shake to solubilize the protein completely. Do not vortex. Reconstituted products should be stored at -80 °. This antibody can also be cross referenced by the term Argenx patent anti-MuSK.
MUSK plays an important and selective role in many aspects of skeletal muscle development and function through the initial step of postsynaptic differentiation and formation of end-plate bands in cooperation with Rapsyn. Communication between cells is often mediated by receptors on the surface of the target cell that are triggered by specific ligands released by other cells. Receptor tyrosine kinase activity is strictly regulated by the binding of the appropriate ligand to the extracellular active site of the receptor. MuSK has been shown to be part of the agrin signaling complex and plays an important role in the development and architectural maintenance of the neuromuscular junction.
Specifications
| MUSK Biosimilar | |
| Recombinant Monoclonal | |
| Unconjugated | |
| Human | |
| 100 μg | |
| Primary | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Lyophilized |
| ELISA, Flow Cytometry, Functional Assay, Surface Plasmon Resonance | |
| 1 mg/mL | |
| 25 mM histidine with 8% sucrose, 0.01% Tween 80 and no preservative; pH 6.2 | |
| Protein A | |
| RUO | |
| Human | |
| Antibody | |
| IgG1 |
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